J S Elborn Selected Research

acebilustat

1/2017	Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction.
1/2017	Phase I Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis.

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J S Elborn Research Topics

Disease

33	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 01/2000
9	Inflammation (Inflammations) 01/2022 - 01/2000
9	Infections 01/2020 - 01/2003
4	Pseudomonas Infections 01/2016 - 05/2000
3	Bronchiectasis 01/2007 - 01/2004
3	Necrosis 03/2004 - 12/2002
2	Lung Diseases (Lung Disease) 01/2014 - 09/2010
2	Chronic Obstructive Pulmonary Disease (COPD) 06/2008 - 07/2007
2	Asthma (Bronchial Asthma) 07/2007 - 12/2002
1	Reinfection 01/2014
1	Bacterial Infections (Bacterial Infection) 01/2010
1	Lung Neoplasms (Lung Cancer) 12/2009
1	Polyps 06/2006
1	Pneumonia (Pneumonitis) 12/2004
1	Bone Resorption 07/2004
1	Burkholderia Infections 10/2001
1	Nasal Septal Perforation 04/2001

Drug/Important Bio-Agent (IBA)

11	Anti-Bacterial Agents (Antibiotics)IBA 07/2011 - 05/2000
5	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2004
5	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2000
5	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2016 - 12/2002
4	CytokinesIBA 12/2004 - 02/2000
3	Pharmaceutical PreparationsIBA 11/2021 - 01/2017
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2010 - 09/2003
3	Interleukin-8 (Interleukin 8)IBA 09/2010 - 12/2002
2	acebilustatIBA 01/2017 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 09/2010 - 09/2003
2	C-Reactive ProteinIBA 09/2010 - 09/2003
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 09/2010 - 09/2003
2	AgarIBA 01/2003 - 10/2001
1	ivacaftorIBA 01/2022
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2022
1	tazobactam drug combination ceftolozaneIBA 01/2018
1	leukotriene A4 hydrolaseIBA 01/2017
1	Tumor Necrosis Factor alpha-Induced Protein 3IBA 02/2016
1	Proteins (Proteins, Gene)FDA Link 01/2016
1	Secretory Leukocyte Peptidase InhibitorIBA 01/2016
1	beta-Aminoethyl Isothiourea (AET)IBA 01/2014
1	Peptide Hydrolases (Proteases)FDA Link 09/2010
1	Type I Tumor Necrosis Factor ReceptorsIBA 09/2010
1	Cathepsin BIBA 09/2010
1	Dithiothreitol (Cleland's Reagent)IBA 01/2010
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2010
1	MicroRNAs (MicroRNA)IBA 01/2010
1	NucleotidesIBA 01/2010
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2010
1	RNA (Ribonucleic Acid)IBA 01/2010
1	Ceftazidime (Fortum)FDA LinkGeneric 11/2007
1	Tobramycin (Nebcin)FDA LinkGeneric 11/2007
1	GlucocorticoidsIBA 07/2007
1	Ribosomal DNA (rDNA)IBA 01/2007
1	1- (2'- tetrahydrothienyl)- 5- fluorouracil- 1'- oxideIBA 01/2007
1	PolyphosphatesIBA 06/2006
1	AcidsIBA 06/2006
1	Phosphates (Orthophosphate)IBA 06/2006
1	Levofloxacin (Levaquin)FDA Link 01/2005
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2005
1	InterleukinsIBA 09/2003
1	TrypsinIBA 12/2002
1	Oxygen (Dioxygen)IBA 04/2001
1	AntigensIBA 03/2000
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2000
1	LipopolysaccharidesIBA 01/2000
1	AntibodiesIBA 01/2000
1	Immunoglobulin G (IgG)IBA 01/2000

Therapy/Procedure

4	Therapeutics 01/2014 - 09/2003
2	Lung Transplantation 01/2015 - 01/2014
1	Intravenous Administration 11/2007
1	Postural Drainage 01/2004
1	Cannula 04/2001
1	Aftercare (After-Treatment) 06/2000